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September 2007 Cover
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A new case report from French researchers appears to debunk a hypothesis that bone marrow transplantation may be a viable method of HIV eradication. The report, published in
AIDS, reviews the case of an adult male
French patient who received a bone-marrow transplant to treat monocytic acute myeloid leukemia. The patient had achieved sustained, undetectable plasma HIV RNA levels while on HAART prior to the transplant; an undetectable
viral load was maintained post-transplant, and researchers also found that HIV DNA levels became undetectable as well, leading them to believe the patient was in "HIV remission." However, HAART was interrupted due to
toxicity concerns 114 days after the transplant. Within 16 days of interruption, HIV RNA and DNA levels had become detectable. The patient ultimately died after developing severe graft-versus-host disease
from TheBodyPro.com
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