|
|
 |
The combination of ritonavir and saquinavir with or without reverse transcriptase inhibitor regimens has been shown to be highly active in numerous clinical studies.
A recent study has shown that the combination of ritonavir and saquinavir demonstrates antiviral synergy (wherein the effect of the combination is greater than the sum of their individual effects) in the test
tube. This finding may explain the profound antiviral effect observed in clinical trials using this regimen. The use of in vitro virological combination data modeled onto observed plasma levels for protease inhibitor
combinations may provide a means for the prediction of the efficacy of dual protease-inhibitor regimens.
Editor's Note: from the 12th World AIDS Conference, Geneva, Switzerland, June 28-July 3
You are not logged in.
No comments yet, but
click here to be the first to comment on this
HIV Digest!
|
