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April 2007 Cover
April 2007 Cover

 HIV Digest HIV Digest Archive  
April 2007 Email this to a friend
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CD4 Floor of 350 for Treatment Start?

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HIV-infected patients who initiate therapy with a CD4 cell count above 350 are far more likely to return to a "nearly normal" CD4 cell count than patients who initiate therapy with a CD4 cell count below 350, according to a study by the Johns Hopkins University School of Medicine. The 655-patient observational study followed patients for a median of 46 months; it found that all patients generally experienced a significant CD4 cell increase during their first year of therapy and eventually plateaued. However, patients who began HAART with a baseline CD4 cell count above 350 had a higher plateau CD4 cell count than patients who began HAART with a baseline CD4 cell count below 350. In their conclusion, the researchers explicitly recommend that HAART initiation be considered while a patient's CD4 cell count is still above 350.

from TheBodyPro.com


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