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February 2007 Cover
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In the last several years, results from large studies have linked the use of some antiretrovirals to a greater risk of cardiovascular complications in HIV-infected patients. The precise role
of HIV and antiretrovirals in the development of these complications has remained a matter of debate, however-- and now, a newly published study appears to establish a causal link
between HIV and atherosclerosis.
The researchers found and elucidated the means by which a protein within HIV can trigger a reduction in a patient's HDL cholesterol levels. "The data support the shift away from a
paradigm of delaying or stopping [antiretroviral therapy] to reduce the risk of cardiovascular disease," the researchers write.
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HIV Digest!
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