September 2008 Cover
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The side effects of AIDS drugs --
including increases in belly fat, elevated blood pressure, and
high triglyceride levels -- are significantly reduced by very small doses of growth hormone, according to the results of a new trial.
However, the treatment raises glucose levels, which may limit the usefulness of the drug for HIV patients.
Previous studies have shown that growth hormone deficiency is very common in HIV-infected patients with abnormal body fat distribution and excessive abdominal fat.
The current trial differed from previous growth hormone studies in HIV patients with treatment-related metabolic effects, because much lower doses were used and the trial lasted much longer at 18 months.
Study results were presented at the International AIDS Conference in Mexico City and were also published in the Journal of the American Medical Association.
from Reuters
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